8194460 Negotiating the Relationship Between Addiction, Ethics, and Brain Science PMC – Periodontist – Meridian, MS

Negotiating the Relationship Between Addiction, Ethics, and Brain Science PMC

Interpreting these and similar data is complicated by several methodological and conceptual issues. First, people may appear to remit spontaneously because they actually do, but also because of limited test–retest reliability of the diagnosis [31]. For instance, using a validated diagnostic interview and trained interviewers, the Collaborative Studies on Genetics of Alcoholism examined the likelihood that an individual diagnosed with a lifetime history of substance dependence would retain this classification after 5 years. Lifetime alcohol dependence was indeed stable in individuals recruited from addiction treatment units, ~90% for women, and 95% for men. In contrast, in a community-based sample similar to that used in the NESARC [27], stability was only ~30% and 65% for women and men, respectively. Diagnosis was stable in severe, treatment-seeking cases, but not in general population cases of alcohol dependence.

  • Likewise National Institute of Mental Health (NIMH’s) Research Domains Criteria framework, which regards psychiatric conditions as disorders of brain circuitry (Insel et al., 2010).
  • The basic premises offered by this model thus provide a foundation to better understand the phenomenology of addiction and develop approaches for its prevention and treatment.
  • They underlined the importance of having access to such treatment and support because it helped them to cope with difficult emotions, thoughts and life situations without using substances, or it provided support to stop using substances after relapses.

Temporomandibular disorder(s)

The sponsor/coach/guide with a vested interest in sobriety is a critical component of any treatment intervention involving addiction. Indeed, this person is absolutely necessary for the establishment of a metacontingency in which the behavior of one individual determines the contingencies for another. Because both individuals are in long-term recovery – these behaviors both feedback and feed forward to maintain the abstinence of both individuals. Moreover, the larger social network of former users – all of whom are in various stages of recovery – encourage one another via modeling and reinforcement to take “personal inventory” and to identify the personal factors that play a causal role in their drug use. In closed meetings, these factors are shared with others – not as an exercise in vulnerability – but to draw attention to the personal factors that contribute to addiction across individuals. The commonality of these personal factors is often unknown to a person just beginning treatment (hence the commonly invoked phrase, “Thank you for sharing”).

Understanding Own Substance Use

The late George Engel believed that to understand and respond adequately to patients’ suffering—and to give them a sense of being understood—clinicians must attend simultaneously to the biological, psychological, and social dimensions of illness. He offered a holistic alternative to the prevailing biomedical model that had dominated industrialized societies since the mid-20th century.1 His new model came to be known as the biopsychosocial model. Engel championed his ideas not only as a scientific proposal, but also as a fundamental ideology that tried to reverse the dehumanization of medicine and disempowerment of patients (Table 1 ▶). His model struck a resonant chord with those sectors of the medical profession that wished to bring more empathy and compassion into medical practice. Mainstream culture in the United States has historically frowned on most substance use and certainly substance abuse (Corrigan et al. 2009; White 1979, 1998). This can extend to legal substances such as alcohol or tobacco (including, in recent years, the increased prohibition against cigarette smoking in public spaces and its growing social unacceptability in private spaces).

biopsychosocial model of addiction

Theorizing personal, interpersonal, and institutional factors in clinical care

Dr. George Engel and Dr. John Romano developed this model in the 1970s, but the concept of this has existed in medicine for centuries. A theory of addiction that borrows principles from social learning and reciprocal determinism provides an approach to addictive behavior that has both philosophical Sober House and practical utility. Addiction professionals tend to partition complex phenomena according to their own self-interests – the neuroscientist sees only neuropathology, the psychologist sees only broken relationships, the bureaucrat sees only ineffective laws and regulations.

I outline in this section two general ways in which post-dualist, cross-disciplinary theories have been developed over recent decades, critical to formulating a biopsychological model. Inpatient SUD treatment was only one step in the recovery process for these informants. They needed support and treatment thereafter—some for short periods and others potentially for the rest of their lives. They talked about the use of substances as isolated incidents or a more regular occurrence. Ethical issues were considered during the recruitment, the interviews, the analysis, and the data interpretation.

Complexity and Causality

biopsychosocial model of addiction

The number of informants was not determined in advance, and we had the option of continuing the recruitment process and including informants even if some data from the main study were lacking. However, during the 11 interviews, the immediate transcriptions, and the ongoing thematic analysis, we obtained 110 pages (55,000 words) of data material. We considered that to be sufficient to answer the research question about how the informants perceived and reflected on the recovery process after they were discharged from inpatient treatment; hence data saturation had been achieved [20, 24]. The informants were recruited by telephone, messenger or mail by one of the researchers.

biopsychosocial model of addiction

Sociodemographic variables and factors

All the informants received some degree of therapy and support from social services or specialised healthcare facilities during the years after inpatient SUD treatment in Tyrili. Three received opioid maintenance https://thearizonadigest.com/top-5-advantages-of-staying-in-a-sober-living-house/ therapy (OMT) and were in contact with a GP or therapist. Eight had been in treatment for trauma, anxiety, depression, psychosis or insomnia, and three had or were waiting for treatment for ADHD.

Genome-wide association studies of complex traits have largely confirmed the century old “infinitisemal model” in which Fisher reconciled Mendelian and polygenic traits [51]. A key implication of this model is that genetic susceptibility for a complex, polygenic trait is continuously distributed in the population. This may seem antithetical to a view of addiction as a distinct disease category, but the contradiction is only apparent, and one that has long been familiar to quantitative genetics. Viewing addiction susceptibility as a polygenic quantitative trait, and addiction as a disease category is entirely in line with Falconer’s theorem, according to which, in a given set of environmental conditions, a certain level of genetic susceptibility will determine a threshold above which disease will arise. Theory is necessary as well as data, of the sort outlined in the first part of the paper.

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